The Accuracy, Night-to-Night Variability, and Stability of Frontopolar Sleep Electroencephalography Biomarkers

The Accuracy, Night-to-Night Variability, and Stability of Frontopolar Sleep Electroencephalography Biomarkers Daniel J. Levendowski, MBA1; Luigi Ferini-Strambi, MD2; Charlene Gamaldo, MD3; Mindy Cetel, MD4; Robert Rosenberg, DO5; Philip R. Westbrook, MD1 1Advanced Brain Monitoring, Carlsbad, California; 2Department of Clinical Neurosciences, San Raffaele Scientific Institute, Sleep Disorders Center, Università Vita-Salute San Raffaele, Milan, Italy; 3Department of [...]

User Compliance and Behavioral Adaptation Associated With Supine Avoidance Therapy

This study investigates behavioral adaptation to vibrotactile position-avoidance therapy during sleep in patients with obstructive sleep apnea (n =135) across 15 to 52 weeks. The overall compliance, based on nights used ≥ 4 hr, was 71%. Overall regular use, that is, ≥ 4 hr/night over 70% of nights, was 88%. Poor early compliance strongly predicted [...]

Modeling temporal sequences of cognitive state changes based on a combination of EEG-engagement, EEG-workload, and heart rate metrics

The objective of this study was to investigate the feasibility of physiological metrics such as ECG-derived heart rate and EEG-derived cognitive workload and engagement as potential predictors of performance on different training tasks. An unsupervised approach based on self-organizing neural network (NN) was utilized to model cognitive state changes over time. The feature vector comprised [...]

Identifying psychophysiological indices of expert vs. novice performance in deadly force judgment and decision making

Johnson RR, Stone BT, Miranda CM, et al. Frontiers in Human Neuroscience 2014;8:512. Objective: To demonstrate that psychophysiology may have applications for objective assessment of expertise development in deadly force judgment and decision making (DFJDM). Background: Modern training techniques focus on improving decision-making skills with participative assessment between trainees and subject matter experts primarily through [...]

Assessment of a Neck-Based Treatment and Monitoring Device for Positional Obstructive Sleep Apnea

The objective of this study was to evaluated the accuracy and efficacy of a neck-worn device designed to limit supine sleep. The study included nightly measurements of snoring, sleep/wake, time supine, and the frequency and duration of feedback to monitor compliance. Thirty patients between ages 18 and 75 years, BMI ≤ 35 with an overall [...]

Development of EEG Biomarkers for Alzheimer’s Disease

The Advanced Brain Monitoring research team partnered with Biogen Idec in a preliminary development of EEG biomarkers using B-Alert X24 equivalent EEG datasets.  Poster was presented at The GTC Biomarker Summit 2014 held March 19-21 in San Diego, CA. Introduction A growing body of evidence suggests that EEG analyses, including both resting state and event-related [...]