Clinical Trial Services

Specializing in early phase studies across neurodegenerative and psychiatric indications

 

Advanced Brain Monitoring offers a full suite of leading edge EEG based sleep and daytime assessment technologies for pharmaceutical, medical device and academic clinical trials.  With expertise across a broad range of neurological disorders, our  neuroscience research team delivers streamlined EEG acquisition, secure management of data integrity, customized data analysis and worldwide clinical support.  In the below introductory overview presentation, CEO & Co-Founder Chris Berka highlights how configurable technologies combined with innovative evidence-based biomarker analyses can serve you as cost effective, noninvasive recruitment or outcome measure.

Neurodegenerative:

Alzheimer’s Disease
Huntington’s Disease
Parkinison’s Disease
Mild Cognitive Impairment
Frontal Temporal Dementia
Lewy Body Dementia

Psychiatric:

Depression
Mood
Schizophrenia
Biopolar
Insomnia

 Services Offered

  • Clinical EEG protocol development and IRB support
  • Options for EEG acquisition to fit your needs:
    • Run studies at ABM facilities
    • Technology “drop shipped” to your study sites anywhere worldwide
  • Certification of new technicians with 6-step, single day process either on-site or via online-remote protocol
  • Devices are FDA-cleared
  • Services are HIPAA and 21 CFR Part 11 compliant including data management via a cloud based portal system
  • Secure, web-based portal provides centralized data management allowing for auditable analyses and timely reporting to sponsor
  • Ongoing data quality feedback to sites as needed
  • Customized quantitative data analysis
  • Quality and timely study reports

Daytime EEG Analysis Capabilities

  • Quantitative EEG (QEEG): Power spectral densities at 1Hz bins or standard bands:
    • Delta 1-4 Hz
    • Theta 4-7 Hz
    • Alpha 8-15 Hz
    • Beta 16-31 Hz
    • Gamma 32-40+
  • Event related potentials (ERP)
  • Low resolution electromagnetic tomography (LORETA)
  • EEG Coherence
  • EEG Phase Delay
  • Alpha anterior/posterior gradients

 moon3 Services Offered

  • Clinical EEG protocol development and IRB support
  • Self-applied in-home or in-lab sleep studies
  • Devices are FDA-cleared
  • Services are HIPAA and 21 CFR Part 11 compliant including data management via a cloud based portal system
  • Ongoing data quality feedback to sites as needed
  • Customized quantitative data analysis
  • Quality and timely study reports

Overnight Analysis Capabilities

  • Sleep Continuity
  • REM w/o Atonia, (we don’t have this in-home yet)
  • Sleep Disordered Breathing
  • REM Latency
  • REM Duration and Density
  • Light NREM
  • Autonomic Activation & Arousals
  • Slow Wave Activity
  • Sleep Quality
  • Spindle Density, Frequency, and Type
  • Head Movement and Position