Roche RG6042 - Biomarker behind the study
Advanced Brain Monitoring is an EEG company internationally recognized for its innovative technologies. Our products are used in clinical trials to interpret brain and physiological function as they relate to disease and drug treatments. ABM provides contract research services with a wireless EEG system administered concurrently with a full suite of tasks, expertise in biomarker development, and implementation for observation and investigational drug clinical trials.
HD reduces EEG brain activity when compared with age- and gender- matched healthy controls.
Tominersen induced a significant increase in power compared to placebo.
The increase in brain activity with tominersen was detectable across dosing levels and was present throughout the duration of the post-treatment EEG monitoring.
There was significant increase in EEG signal power in patients treated with tominersen compared with patients treated with placebo.